Quantitative Susceptibility Mapping (QSM)


QSM enables the investigation of tissue magnetic susceptibility in a quantitaive and specific manner using magnetic resonance imaging (MRI). QSM is useful for identification and quantification of specific biomarkers including iron, calcium, gadolinium, and super paramagnetic iron oxide (SPIO) nano-particles. Due to its specificity, QSM is more sensitive to nuance differences in susceptibility that may be otherwise overriden by relaxation effect. The quantitative nature faciliates longitudinal investigations or multi-center comparison studies.

Although susceptibility effect, among relaxation and motion, is a major pillar for contrast generation in MRI, imaging susceptibility was often complicated by the blooming artifact, ambiguitiy created by both para- and diag- magnetism, and arbitrariness caused by imaging or post-processing parameters, hindering a definitive assessment. Now, QSM provides an integrated solution to these technical pitfalls. Learn the tricks