QSMetric™

FDA 510(k) cleared.

QSMetric™ processes gradient echo images of the brain, and when used in combination with other clinical information, aids the qualified physicians in visualizing tissue structures with magnetic susceptibility contrasts and measuring their susceptibility values.

How are clinicians using QSMetric™ in their practices

Our QSMetric™ product is cleared for use under a tool-type indication as stated above. However, physicians are using this product in their clinical practices on a daily basis as supported by studies published in the peer-reviewed medical literature. Here are a few examples of how QSMetric™ is benefiting clinicians and their patients.

Functional iron in the brain

QSM can map iron involved in neuron function, including neurotransmitter generation and oxygen consumption. Deep gray nuclei are highly active in neurotransmitter generation with iron as a cofactor.

Targeting for DBS

QSM can map iron involved in neuron function, including neurotransmitter generation. Deep gray nuclei are highly active in neurotransmitter generation with iron as a cofactor. Traditional T2 weighted imaging (left) depicts iron-rich deep gray nuclei such as subthalamic nucleus (arrow) with blurred hypointensity. QSM (right) depicts subthalamic nucleus with sharp positive contrast. QSM is the method of choice for mapping DBS targets.

Pathological iron in the brain

Measure hemorrhages, including cerebral cavernous malformation (CCM) and microbleeds. QSM is a quantitative biomarker for monitoring CCM disease activity and response to treatments. Traditional MRI (T2 weighted, below left) does not provide a quantitative measure of bleeding in CCM. QSM (below right) provides a quantitative measure of the total magnetic moment for monitoring the CCM lesion.

Differentiate calcifications from hemorrhages

Traditional T2* weighted gradient echo magnitude or susceptibility weighted imaging (SWI) images (left) display both calcifications and hemorrhages with indistinguishable hypointensity. QSM (right) displays calcifications with negative values (dark arrow) and hemorrhages with positive values (white arrow).

Monitor neuroinflammation